• Staff members
• Project Summary
• Publications

Publications

Selected Publications

• Hahn H; Wicking C; Zaphiropoulos P; Gailani M; Shanley S; Chidambaram A; Vorechovsky I; Holmberg E; Unden A; Gillies S; Negus K; Smyth I; Pressman C; Leffell D; Gerrard B; Goldstein A; Wainright B; Toftgard R; Chenevix-Trench G; Dean M; Bale A. Mutations of the human homologue of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996 June14; 85(6): 841-51.
• Hahn H; Wojnowski L; Zimmer AM; Hall J; Miller G; Zimmer A. Rhabdomyosarcomas and radiation hypersensitivity in a mouse model for Gorlin syndrome. Nat Medicine 1998 May; 4(5): 619-622.
• Uhmann A; Dittmann K; Nitzki F; Dressel R; Koleva M; Frommhold A; Zibat A; Binder C; Adham I; Nitsche M; Heller T; Armstrong V; Schulz-Schaeffer W; Wienands J; Hahn H. The Hedgehog receptor Patched controls lymphoid lineage commitment. Blood 2007 Sep 15;110(6):1814-23.
• Ecke I; Petry F; Rosenberger A; Tauber S; Mönkemeyer S; Hess I; Dullin C; Kimmina S; Pirngruber J; Johnsen SA; Uhmann A; Nitzki F; Wojnowski L; Schulz-Schaeffer W; Witt O; Hahn H. Antitumor effects of a combined 5-aza-2’deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice. Cancer Research 2009 69:887-95.
• Nitzki F; Zibat A; König S; Wijgerde M; Rosenberger A; Brembeck F; Carstens PO; Frommhold A; Uhmann A; Klingler S; Reifenberger J; Pukrop T; Aberger F; Schulz- Schaeffer W; Hahn H. Tumor stroma-derived Wnt5a induces differentiation of basal cell carcinoma of Ptch mutant mice via CaMKII. Cancer Research 2010 Apr 1;70(7):2739-48.
• Zibat A; Uhmann A; Nitzki F; Wijgerde M; Frommhold A; Heller T; Armstrong V; Wojnowski L; Quintanilla-Martinez L; Reifenberger J; Schulz-Schaeffer W; Hahn H
  Time-point and dosage of gene inactivation determine the tumor spectrum in conditional Ptch knockouts
  Carcinogenesis 2009 30(6):918-26.